ESCLERODERMIA EN PEDIATRIA PDF

Published studies are primarily clinical and epidemiological research but also basic. CiteScore measures average citations received per document published. Read more. SRJ is a prestige metric based on the idea that not all citations are the same.

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Published studies are primarily clinical and epidemiological research but also basic. CiteScore measures average citations received per document published. Read more. SRJ is a prestige metric based on the idea that not all citations are the same.

SJR uses a similar algorithm as the Google page rank; it provides a quantitative and qualitative measure of the journal's impact. SNIP measures contextual citation impact by wighting citations based on the total number of citations in a subject field. Scleroderma is an autoimmune disease that involves the connective tissue characterized by skin fibrosis, classified as localized and systemic participation of one or more internal organs.

The primary objective of this study is to describe and analyze the clinical and laboratory findings in a group of children diagnosed with scleroderma at a referral hospital.. Sixty-two patients were included in the group. All of them completed the classification criteria for juvenile sclerodema, both systemic and localized. The mean age at diagnosis was 7. The mean time from disease onset to diagnosis, based on clinical manifestations, was 23 months. The most common drug used was methotrexate..

The most common skin lesions found were linear morphea, followed by the mixed and circumscribed types. In systemic scleroderma the most involved systems are the gastrointestinal, respiratory, and vascular associated with Raynaud's phenomenon.

There is a special need for knowledge of this disease in first contact physicians for a faster and better diagnosis and treatment, in order to avoid complications. It is also necessary to improve resources in developing countries for complimentary studies, classification, treatment, and follow-up.. ISSN: Open Access Option. Previous article Next article. Issue 4. Pages July - August Clinical characteristics of children with scleroderma in a referral hospital. Download PDF.

Zoilo Morel. Corresponding author. This item has received. Article information. Introduction Scleroderma is an autoimmune disease that involves the connective tissue characterized by skin fibrosis, classified as localized and systemic participation of one or more internal organs. The primary objective of this study is to describe and analyze the clinical and laboratory findings in a group of children diagnosed with scleroderma at a referral hospital.

Results Sixty-two patients were included in the group. The most common drug used was methotrexate. Conclusion The most common skin lesions found were linear morphea, followed by the mixed and circumscribed types. It is also necessary to improve resources in developing countries for complimentary studies, classification, treatment, and follow-up. Systemic scleroderma. Palabras clave:. Full text is only aviable in PDF. Roberts Thomson, J.

History in medicine. Scleroderma: It has been a long hard journey. Internal Medicine Journal, 36 , pp. Coyle W. A brief history of scleroderma.

LeRoy, C. Black, R. Fleischmajer, S. Jablonska, T. Medsger TA. Scleroderma systemic sclerosis : Classification, subsets and pathogenesis. J Rheumatol, 15 , pp. Zulian, P. Woo, B. Athreya, R. Laxer, T. Medsger, T. Laxer, F. Curr Opin Rheumatol, 18 , pp. Rheumatology, 45 , pp. Systemic sclerosis and localized scleroderma in childhood. Rheum Dis Clin N Am, 34 , pp. Martini, I.

Foeldvari, R. Russo, R. Cuttica, A. Eberhard, A. Ravelli, et al. Systemic sclerosis in childhood: Clinical and immunological features of patients in an international database.

Arthritis Rheum, 54 , pp. Tollefson, P. En coup de sabre morphea and Parry-Romberg syndrome: A retrospective review of 54 patients. J Am Acad Dermatol, 56 , pp. Zulian, B. Laxer, A. Nelson, S. Feitosa de Oliveira, M. Punaro, et al. Juvenile localized scleroderma: Clinical and epidemiological features in children. An international study. Pavlov Dolijanovic, N. Damjanov, P. Ostojic, G.

Susic, R. Stojanovic, D. Gacic, et al. The prognostic value of nailfold capillary changes for the development of connective tissue disease in children and adolescents with primary Raynaud phenomenon: A followup study of patients. Pediatric Dermatology, 23 , pp.

Subscribe to our newsletter. Print Send to a friend Export reference Mendeley Statistics. Recommended articles. Clinical impact of nailfold capillaroscopy in daily Cutaneous lupus erythematosus, morphea profunda and Methotrexate in Patients With Rheumatoid Arthritis in Instructions for authors Submit an article Ethics in publishing.

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Revista de la Facultad de Medicina

The multifactorial etiology of this disease is related to alterations in remodeling interactions of the extracellular matrix ECM , immune function and presence of proliferative vasculopathy under genetic and environmental influence. Incidence and prevalence of systemic sclerosis: a systematic literature review. Semin Arthritis Rheum. Rev Bras Reumatol.

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Esclerodermia

La esclerodermia localizada afecta la piel. Se desconoce la causa exacta de la esclerodermia. Todo esto ayuda a determinar si tiene esclerodermia. Los posibles tratamientos incluyen medicamentos, como cremas para la piel o cambios en la dieta y el estilo de vida. No hay cura para la esclerodermia.

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