FREE subscriptions for doctors and students Virginal or juvenile breast breast hypertrophy is a rare and distinct disorder with the rapid onset of macromastia at the onset of puberty. Most patients with macromastia have breasts which develop normally at puberty but simply reach excessive size 1,2. One review revealed that patients were reported in the medical literature between and , and amongst these, 57 had a clear diagnosis of juvenile gigantomastia 2.
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Juvenile gigantomastia is a benign disorder of the breast in which one or both of the breasts undergo a massive increase in size during adolescence. The authors present a series of four cases of juvenile gigantomastia, advances in endocrine management, and the results of surgical therapy. Three patients were treated for initial management of juvenile gigantomastia and one patient was evaluated for a gestationally induced recurrence of juvenile gigantomastia.
The three women who presented for initial management had a complete evaluation to rule out other etiologies of breast enlargement. Endocrine therapy was used in 2 patients, one successfully. A year-old girl had unilateral hypertrophy treated with reduction surgery. She had no recurrence and did not require additional surgery. Two patients, ages 10 and 12 years, were treated at a young age with reduction mammaplasty, and both of these girls required secondary surgery for treatment.
One patient underwent subtotal mastectomy with implant reconstruction but required two subsequent operations for removal of recurrent hypertrophic breast tissue. The second patient started a course of tamoxifen followed by reduction surgery. While on tamoxifen, the second postoperative result remained stable, and the contralateral breast, which had exhibited some minor hypertrophy, regressed in size.
The fourth patient was a gravid year-old who had been treated for juvenile gigantomastia at age 14, and presented with gestationally induced recurrent hypertrophy. The authors' experience has been that juvenile gigantomastia in young patients is prone to recurrence, and is in agreement with previous studies that subcutaneous mastectomy provides definitive treatment.
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Send even when there aren't any new results. Optional text in email:. Save Cancel. Create a file for external citation management software Create file Cancel. Full-text links Cite Favorites. Abstract Juvenile gigantomastia is a benign disorder of the breast in which one or both of the breasts undergo a massive increase in size during adolescence. Similar articles Management of gestational gigantomastia. Swelstad MR, et al. Plast Reconstr Surg. PMID: Review. J Pediatr Adolesc Gynecol. Epub Apr PMID: Juvenile gigantomastia.
Samuelov R, Siplovich L. Samuelov R, et al. J Pediatr Surg. Pregnancy-associated gigantomastia recurrence and ectopic breast after reduction mammaplasty: A case report.
Zhou M, et al. Cancer Biomark. Virginal mammary hypertrophy: a meta-analysis and treatment algorithm. Hoppe IC, et al. Show more similar articles See all similar articles. J Breast Health. Hisham A, et al. Case Rep Surg. Epub Jan Nonsurgical management of fibroadenoma and virginal breast hypertrophy. Pruthi S, Jones KN. Pruthi S, et al. Semin Plast Surg. Hyperplastic breast anomalies in the female adolescent breast.
Wolfswinkel EM, et al. Gestational gigantomastia with complete resolution in a Nigerian woman. Ezem BU, et al. BMJ Case Rep. Show more "Cited by" articles See all "Cited by" articles. Publication types Case Reports Actions. Review Actions. MeSH terms Adolescent Actions. Adult Actions. Breast Implants Actions. Child Actions. Female Actions. Humans Actions. Hypertrophy Actions. Pregnancy Actions. Recurrence Actions. Substances Estrogen Antagonists Actions.
Tamoxifen Actions. Full-text links [x] Wolters Kluwer. Copy Download.
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Juvenile gigantomastia: Report of a case
Juvenile Gigantomastia in a 12-year-old Girl: A Case Report
We'd like to understand how you use our websites in order to improve them. Register your interest. Juvenile gigantomastia is a rare, massive breast enlargement. It appears in adolescence and can affect one or both breasts of otherwise healthy girls. This report describes a case of a bilateral and symmetric gigantomastia in a year-old girl.